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ATF3 gene could be the crucial web page link between stress and breasts cancer: Study In an unexpected selecting, scientists have linked the activation of a strain gene in immune-system cells to the spread of breast cancer to other parts of the body. Researchers say the scholarly study suggests this gene, called ATF3, could be the crucial link between stress and tumor, including the major cause of cancer death – its pass on, or metastasis. Previous public health studies have shown that tension is a risk aspect for cancer. Researchers know that ATF3 is activated currently, or expressed, in response to demanding conditions in all types of cells. Under usual circumstances, turning on ATF3 can actually cause normal and benign cells to commit suicide if the cells decide that the stressors, such as for example irradiation and too little oxygen, have irrevocably broken the cells.