Whenever we looked at length at IVF and ICSI, the odds ratio for birth defects associated with IVF was 1.26 in unadjusted analyses and 1.07 after multivariate adjustment; corresponding odds ratios associated with ICSI were 1.77 and 1.57 . As compared with ICSI, IVF was connected with a reduced threat of any birth defect . Assisted conception that didn’t involve gamete manipulation , reflecting presumably less invasive types of assisted reproductive technology, was also connected with an increased risk of any birth defect .Binge drinking is a concern because it’s very likely that those women are exposing their kids to alcohol on a regular basis, said Dr. Jennifer Wu, an obstetrician and gynecologist at Lenox Hill Medical center in NEW YORK. Females who are binge drinking perform tend to drink more frequently, Wu stated. They will continue that throughout the pregnancy. Among women that are pregnant, alcohol use was highest among those aged 35 to 44 , college graduates and unmarried women , the investigators found. There are mixed messages on the subject of drinking during pregnancy that may lead some women to believe it’s OK to use alcohol, Tan said.